Cytotoxic drugs can be taken as tablets or given as an injection and infusion. For the treatment of some cancers of the skin are also suitable ointment preparations.
This application forms, however, are not arbitrarily interchangeable: Only a few diseases such as situations are currently available for oral cytotoxics. Most cancer patients receiving chemotherapy through an infusion into a vein. The following text will give an overview of the various application forms and explain some commonly used terms. Which means, as applied in individual cases will need to discuss patients with their treating physicians.
As the example shows p53, which is simply testing the various forms of chemotherapy resistance in practice. To date, no chemosensitivity testing in routine proved to cancer patients.
This is particularly true for the products of many commercial vendors that offer patients an appropriate diagnosis for a fee. Here are often advertised with the supposedly rapid implementation of the latest research results - whether the tests are worth the cost, most insurance companies do not reimburse the remains questionable.
To assess whether chemotherapy is likely to contribute or not presently covered by the data from clinical trials to be more reliable.
The importance of individual assessment of tumor biology and the testing of genetic characteristics of a tumor before treatment started, but changes: New technical solutions make it increasingly possible to test many properties of tumor cells within a short time, yet cost-effective. Has such a test to assess its usefulness of prognostic factors were shown once, it will be included in the framework of recommendations and medical guidelines, patients must then no longer have to worry about it that it is conducted, or even pay for it themselves.
Beginning to a patient develops a resistance to emerge and walks his illness persists despite chemotherapy, may, depending on the situation, bring the bill to another agent but still successful. In the future, a new generation of drugs to alleviate the problem of resistance development, which is addressed more specifically than cytotoxic against tumor cells.
More on the new molecular biological methods of cancer diagnosis and the ensuing "Targeted Therapies read", A fact sheet provides concise information about downloading and printing.
Chemotherapy, chemotherapy sensitivity and resistance: Why do some tumors do not respond?
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What happens when a tumor continues to grow despite treatment? Insensitive to chemotherapy, cancer cells through many different processes can be or. Some of them are based on detoxification mechanisms. Other tumors do not respond to cytotoxic drugs, because they went the ability to natural cell death, apoptosis, is lost. What are the mechanisms of the so-called resistance are known so far and why chemosensitivity testing currently in practice make little sense to show the Cancer Information Service at the following text.
Detoxification - not desirable in cancer
The chemotherapy has improved treatment options for cancer in recent decades: Affected, which were once considered largely incurable, can now often look hopefully to the future, as young men with testicular cancer or children with leukemia. Cytostatics play as adjutant or complementary therapy in many cancers, a growing role in order to avoid relapses. Nonadjustable, prior surgery, chemotherapy can make some huge inoperable tumor in the first place.
Actually, the term refers to any type of chemotherapy drug treatment, should be placed in the cells to die off or prevented from growing. The pathogen can also be like cancer cells. In a broader sense are equally applicable to antibiotics as "chemotherapy".
For about 60 years are used for cytotoxic chemotherapy for cancer. Simplified translated the term cytostatic "cell stopper means": Such substances prevent cells at the division and put them to death. Many cytotoxic drugs to put on to the genetic material. Others block important metabolic processes in cell division. Because these are very basic operations that contribute almost all cellular toxins, not only on cancer cells: Does are - to varying degrees - all the fast-regenerating tissue. Typical side effects of many cytotoxic drugs are therefore temporary impairment of blood cell formation, or even hair loss. Nausea and vomiting, much feared by many patients, can now be largely suppressed by concomitant medications.
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